The Co Laboratory

Discovering New Concepts in Interfacial Reaction and Engineering for
Template Synthesis of Nanomaterials, Encapsulation, and Dynamic Control of Cell-Biomaterial Interfaces

Carlos Co
Assistant Professor
Chemical and Materials Engineering
Room 566 ERC
University of Cincinnati
Cincinnati, OH 45221-0012
Tel: (513) 556-2731
Fax: (513) 556-3473
Email: carlos.co@uc.edu

 

 

 

Research Activities

Complex Glasses
Anhydrous sugar-based microemulsions and liquid-crystalline phases in the solid glass state.  Solid sugar nanostructures are robust templates, resisting rearrangement during reactions, but are readily dissolved in water afterwards.
Featured in The New York Times - 03Apr2007
NSF CAREER Award 2007

Liquid-Core Capsules
Encapsulation of sub-micron (<300 nm) oil or water drops through interfacial free-radical alternating copolymerization of hydrophobic and hydrophilic monomers - a free-radical analogy of the nylon rope trick.

Cell - Biomaterial Interfaces
Dynamic switching of interfaces between cell-adhesive and cell-resistant states to study cell motility and control the spatial assembly of multiple cell types.

Selected Publications

Alternating Polymer Vesicles, D Wu, L Abezgaus, D Danino, CC Ho, and CC Co, Soft Matter, 2008, 4, 1066-1071. [pdf]

Arresting Amphiphilic Self-Assembly, CC Co, Soft Matter, 2008, 4, 658-662. [pdf]

Self-Assembly in Sugar-Oil Complex Glasses, H Dave, F Gao, M Liberatore, JH Lee, CC Ho, and CC Co, Nature Materials, 2007, 6, 287-290. [pdf]

Guiding Cell Migration Using One-Way Micropattern Arrays, G Kumar, CC Ho, and CC Co, Advanced Materials, 2007, 19, 1084-1090. [pdf]

Polymerization in Bicontinuous Microemulsion Glasses. F Gao, CC Ho, and CC Co, Macromolecules, 2006, 39, 9467-9472. [pdf]

Aqueous-Core Capsules via Interfacial Free Radical Alternating Copolymerization. D Wu, C Scott, CC Ho, and CC Co, Macromolecules, 2006, 39, 5848-5853. [pdf]

Cell Motility Assays on Tissue Culture Dishes via Non-Invasive Confinement and Release of Cells. G Kumar, JJ Meng, W Ip, CC Co, and CC Ho, Langmuir, 2005, 21, 9267-9273. [pdf]

Altering SH-SY5Y (Human Neuroblastoma Cells) Morphology on Micropatterned Culture Dishes. IH Yang, CC Lin, CC Co, and CC Ho, Biomaterials, 2005, 26, 6599-6609. [pdf]

Liquid-Core Capsules via Interfacial Polymerization: A Free-Radical Analogy of the Nylon Rope Trick.  C Scott, D Wu, CC Ho, and CC Co, J. Am. Chem. Soc., 2005, 127, 4160-4161. [pdf]

Micropatterning Proteins and Cells on Polylactic Acid and Poly(lactide-co-glycolide).  CC Lin, CC Co, and CC Ho, Biomaterials, 2005, 26, 3655-3662. [pdf]

Biocompatible Micropatterning of Two Different Cell Types.  CC Co, YC Wang, and CC Ho, J. Am. Chem. Soc., 2005, 127, 1598-1599. [pdf]

Sugar-Based Microemulsion Glass Templates.  F Gao, CC Ho, and CC Co, J. Am. Chem. Soc., 2004,  126, 12746-12747. [pdf]

Microemulsification of Triglyceride Sebum and the Role of Interfacial Structure on Bicontinuous Phase Behavior.  L Huang, A Lips, and CC Co, Langmuir, 2004, 20, 3559-3563. [pdf]

 

All publications

Group Members

Principal Investigator
Prof. Carlos C. Co

Former Undergraduate Students

Kimberly Ortiz
Brad Bessler
Andrew Swaney
Ashley Lindemuth
James Bowen
Christopher Babel
Christopher Mosko
Lyle Fait
James Hancock
Jennifer Kichler
James Ring
Shanna Smith
Jeffrey Ackerman
Jonathan Burkhardt
Brandon Hughes
Daniel Mulligan

Postdoctoral Fellow
Carl Scott
Graduate Students
Feng Gao
Dan Wu
Hiteshkumar Dave
Stephen Fenimore
Brian Schoop

 

Education

Computational Software

Awards

  • BP Amoco Faculty Teaching Excellence Award (2005)
  • University of Cincinnati College of Engineering Tribunal Professor of the Quarter (Autumn 2004)
  • BP Amoco Faculty Teaching Excellence Award (2003)

 

This site was last updated 04/29/08